Blar i forfatter "Chen, Xiangjun"

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    • Coma influence on manifest astigmatism in coma-dominant irregular corneal optics 

      Zhou, Wen; Stojanovic, Filip; Reinstein, Dan Z.; Archer, Timothy J.; Chen, Xiangjun; Feng, Yue; Stojanovic, Aleksandar (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-01)
      PURPOSE:To evaluate the influence of coma on manifest refractive cylinder (MRC) in eyes with coma-dominated corneal optics and suggest alternative guidelines for surgical planning of astigmatism correction in topography-guided ablation and toric intraocular lens (IOL) exchange surgery.<p> <p>METHODS:Twelve eyes with coma-dominant corneal optics and low lenticular astigmatism were selected. The ...

    • Heidelberg Anterion Swept-Source OCT Corneal Epithelial Thickness Mapping: Repeatability and Agreement With Optovue Avanti 

      Feng, Yue; Reinstein, Dan Z.; Nitter, Tore A.; Archer, Timothy J.; McAlinden, Colm; Chen, Xiangjun; Utheim, Tor Paaske; Bertelsen, Geir; Stojanovic, Aleksandar (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-01)
      <p><b> PURPOSE:</b> To assess the repeatability of corneal epithelial thickness mapping in virgin, post-laser refractive surgery (PLRS), and keratoconic eyes using a novel swept-source optical coherence tomographer (SS-OCT), and to determine the agreement of the measurements with a validated spectral-domain (SD) OCT. <p><b> METHODS:</b> Analysis of 90 virgin, 46 PLRS, and 122 keratoconic eyes ...

    • Identifying Important Proteins in Meibomian Gland Dysfunction with Explainable Artificial Intelligence 

      Storås, Andrea; Magnø, Morten Schjerven; Fineide, Fredrik; Thiede, Bernd; Chen, Xiangjun; Strumke, Inga; Halvorsen, Pål; Utheim, Tor Paaske; Riegler, Michael Alexander; Jensen, Janicke L.; Galtung, Hilde (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-17)
      Meibomian gland dysfunction is the most common cause of dry eye disease and leads to significantly reduced quality of life and social burdens. Because meibomian gland dysfunction results in impaired function of the tear film lipid layer, studying the expression of tear proteins might increase the understanding of the etiology of the condition. Machine learning is able to detect patterns in ...

    • Intraoperative swept-source OCT–based corneal topography for measurement and analysis of stromal surface after epithelial removal 

      Zhou, Wen; Reinstein, Dan Z.; Archer, Timothy J.; Chen, Xiangjun; Utheim, Tor Paaske; Feng, Yue; Stojanovic, Aleksandar (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-01)
      <p>PURPOSE: To assess intraoperative stromal topography measurements using swept-source optical coherence tomography (OCT)–based topography/tomography after epithelial removal and to analyze the epithelial contribution to the corneal topography and optics. <p>METHODS: This was a prospective series of 22 eyes of 19 patients referred to receive phototherapeutic keratotomy (PTK) for treatment of ...

    • Predicting an unstable tear film through artificial intelligence 

      Fineide, Fredrik; Chen, Xiangjun; Magnø, Morten Schjerven; Yazidi, Anis; Riegler, Michael; Utheim, Tor Paaske; Storås, Andrea Marheim (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-10)
      Dry eye disease is one of the most common ophthalmological complaints and is defined by a loss of tear film homeostasis. Establishing a diagnosis can be time-consuming, resource demanding and unpleasant for the patient. In this pilot study, we retrospectively included clinical data from 431 patients with dry eye disease examined in the Norwegian Dry Eye Clinic to evaluate how artificial intelligence ...

    • Safety and efficacy of epithelium-on corneal collagen cross-linking using a multifactorial approach to achieve proper stromal riboflavin saturation 

      Stojanovic, Aleksandar; Chen, Xiangjun; Jin, Nan; Zhang, Ting; Stojanovic, Filip; Ræder, Sten; Utheim, Tor Paaske (Journal article; Tidsskriftartikkel; Peer reviewed, 2012-07-30)
      Purpose. To evaluate the efficacy and safety of epithelium-on corneal collagen cross-linking (CXL) using a multifactorial approach to achieve proper stromal riboflavin saturation. Methods. This non-randomized retrospective study comprised 61 eyes with progressive keratoconus treated with epithelium-on CXL. Chemical epithelial penetration enhancement (benzalkonium chloride-containing local medication ...

    • Using machine learning model explanations to identify proteins related to severity of meibomian gland dysfunction 

      Storås, Andrea; Fineide, Fredrik; Magnø, Morten Schjerven; Thiede, Bernd; Chen, Xiangjun; Strumke, Inga; Halvorsen, Pål; Galtung, Hilde; Jensen, Janicke Cecilie Liaaen; Utheim, Tor Paaske; Riegler, Michael Alexander (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-22)
      Meibomian gland dysfunction is the most common cause of dry eye disease and leads to significantly reduced quality of life and social burdens. Because meibomian gland dysfunction results in impaired function of the tear film lipid layer, studying the expression of tear proteins might increase the understanding of the etiology of the condition. Machine learning is able to detect patterns in complex ...